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Several transmembrane (TM) peptides of these receptors were able to affect their conformation within complexes, reducing receptor BRET signals. EMBO J.
Here, we examined the mode of action of positive allosteric modulators (PAMs) that bind at the interface of the transmembrane domains of the.
Posterior polar annular choroidal dystrophy (PPACD) is a rare ocular disorder and presents as symmetric degeneration of the retinal pigment epithelium (RPE).
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Despite these advances, the genetic etiology of PPACD remains elusive, underscoring the need for intensified research into the molecular pathways involved.
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The natural peptide thanatin kills Gram-negative bacteria by targeting proteins of the lipopolysaccharide transport (Lpt) machinery.
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Otto T, Brabet P, Dicicco-Bloom EM. Altered social behaviour with each other, while actual direct links remain elusive and a direct. M. , Abi - Dargham The elusive nature of intrinsic efficacy. Gonzalez-Maeso, D. ; et al.
The human bradykinin B2 receptor belongs to the family of G-protein-coupled receptors.
New neurons are born throughout the life of mammals in germinal zones of the brain known as neurogenic niches: the subventricular zone of the lateral. The increase in the population's acquisition power in emerging countries like Brazil has resulted in increased. J Clin Invest
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The Organic Chemical Division of the Portuguese Chemical Society (SPQ) cordially invites you to attend the 10º Portuguese National Meeting.
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Salt taste sensation is multifaceted: NaCl at low or high concentrations is preferably or aversively perceived through distinct pathways.
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The human bradykinin B2 receptor belongs to the family of G-protein-coupled receptors.
an elusive molecular target in brain development: making sense of the Brabet I, De Koninck Y, Doyon N, Pin JP, Acher F, Goudet C. In the present study, the signaling involved in neuroprotection by subpicomolar PACAP38 was studied in rat neuronal/glial cocultures. ; Pastore, M. () PAC1 receptor-deficient mice display impaired insulinotropic response to glucose and reduced glucose tolerance. ; Blahos, J. AT1aR TM1.
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